Sentence examples for a considerable clinical problem from inspiring English sources

Pressure ulcer represents a considerable clinical problem.

Unfortunately, taxane resistance is a considerable clinical problem, and overcoming this is a key step to improving breast cancer patient survival.

Malignant melanoma, being the most aggressive form of skin cancer, represents a considerable clinical problem worldwide, where about 1 : 35 Caucasians will suffer from malignant melanoma during their lifetime with an incidence furthermore accelerating (Lens and Dawes, 2004).

Although penicillin-resistant S. pyogenes has never been observed to date, the increasing rates of macrolide-resistant group A streptococci (MRGAS) pose considerable clinical problems in many countries (4 ).

Postoperative effusions and edema and capillary leak syndrome in children after cardiac surgery with cardiopulmonary bypass constitute considerable clinical problems.

Both infection and MDR result in a considerable clinical and economic burden.

Although the incidence and mortality associated with NVUGIB have been decreasing owing to considerable advances in the prevention and management of NVUGIB over the past 20 years, it remains a common clinical problem with an annual incidence of ∼67 per 100,000 individuals in the United States in 2012.

Wear of total hip prosthesis is a significant clinical problem that nowadays involves a growing number of patients.

Third, suicide is a huge clinical problem.

Neuropathic pain remains a pressing clinical problem.

Despite being both a major clinical problem and a focus of research for the critical care community, ARDS remains difficult to define and a source of considerable controversy [ 4- 7].