Sentence examples for a considerable change for from inspiring English sources

However, cost-effectiveness is explicitly absent from NICE's existing Interventional Procedures Programme where device-related procedures have been typically submitted for evaluation before the existence of the MTEP, so this is a considerable change for manufacturers of medical devices.

Apple typically makes smaller purchases of startups and companies most people have never heard of, so Beats is a considerable change of course for the company.

Commanding a pursuit group involved a considerable change of pace for a man whose career thus far had been spent in bombers.

In the presence of carbonate phase, a considerable change in microstructure for the densification of BZY electrolytes sintered at 670 °C for 4 h is clearly visible in SEM analysis.

It's hardly the first time that Amazon has sought to position its tablets as a strong competitor to the iPad — Amazon CEO Jeff Bezos noted in an interview with AllThingsD that he felt the 8.9-inch Kindle Fire HD was "the best tablet at any price" — but this move represents a considerable change in tone for Amazon.

Transit is part of Montreal-based accelerator FounderFuel's current cohort, and FounderFuel's GM Ian Jeffrey says that they're happy to see the app really "catching fire" since introducing this update, which represents a considerable change in strategy for the app.

In particular, dropping the second lag of the unemployment variable (column 4) leads to a considerable change in the regression coefficient for the first lag of cyclical unemployment but the coefficient for the fiscal policy variable is not substantially affected.

The mere fact that the visits took place -- and Mr. Bloomberg's easy-going banter with two labor leaders who just three days ago were working against his election -- suggests, at least for now, a considerable change in tone in the way City Hall will be dealing with unions.

Under the right circumstances, small changes in Na+ channel kinetics can cause a considerable change in the number of channels available for generation of action potentials as steady-state inactivation controls the number of channels that can be opened (Van Petegem et al. 2012).

Approximately half a million children and young people undergo anaesthesia and surgery each year in England and Wales. 1 There has been a considerable change in the delivery of surgical services for children in the UK over the past 20 years.

However, for the LJ, there was a considerable change in the composition between LJ 1 and LJ 2 (Table 6).