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Reception of television programming while on the road is a considerable challenge; the broadcasts were never designed to be picked up in a moving vehicle.
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Of her death, New Delhi correspondent William K. Stevens wrote "Her sudden disappearance from the public scene represents a considerable challenge to the future of the Indian experiment in democracy".
Connect to Today: As her obituary also noted, domestically, Indira Gandhi's government "made limited headway against such age-old Indian problems as overpopulation, hunger, caste, inadequate sanitation and chronic religious strife among the majority Hindus, Moslems and other sects" and that her death represented a "considerable challenge to the future of the Indian experiment in democracy".
The process has been a considerable challenge and the mission is far from accomplished, partly because the practice was so ingrained in military culture.
The microenvironment in the bone metastases poses a considerable challenge for the infiltrating CAR T cells (see Fig. 2).
On the Republican side, Ms. Whitman would face a considerable challenge from the state insurance commissioner, Steve Poizner, one of the few in his party to win statewide office recently.
A considerable challenge in the analysis is constituted by the presence of heterozygous mutations, which in M2s are expected to be 2/3 of the mutant sites.
Soft tissue management around the lower third of the leg and foot presents a considerable challenge to the plastic surgeon.
The extent of the surgery such as CUTE represents a considerable challenge to the patient, surgeon, and anesthesiologist.
The relatively poor experimental tractability of many of the organisms within the additional eukaryotic super-groups poses a considerable challenge, but the availability of genome sequences from some of these taxa can facilitate rapid identification of factors in such systems.
That gives the industry a very high responsibility to ensure the consumer chooses the right products and ingredients for his/her health – a considerable challenge given the plethora of ingredients available and used in combination, the huge amount of data with (are they sufficiently reliable?), the challenge of traceability of ingredients, and the difficulties for risk assessment.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com