Sentence examples for a considerable challenge as from inspiring English sources

Numerical simulation of solids production presents a considerable challenge as intricacies of breakout processes must be correctly simulated in order to correctly predict rates of solids production.

The provision of many essential multiprotein complexes of higher eukaryotes including humans, can be a considerable challenge, as low abundance and heterogeneity often rule out their extraction from native source material.

The characterization of pDC lineage has presented a considerable challenge, as pDC display molecular markers and features of several cell types and can be derived from multiple progenitors.

Estimating the disease prevalence and test accuracy (sensitivity and specificity) for two dependent screening tests when the status of individuals who are negative on both tests is unverified represents a considerable challenge, as the disease rates for individuals negative on both tests are not identifiable without additional assumptions.

Estimating the disease prevalence and test accuracy (sensitivity and specificity) when the two tests are dependent and when individuals negative on both tests are unverified is a considerable challenge, as the disease rate for individuals who are negative on both tests is not identifiable without additional assumptions [ 5– 9].

82 This is a considerable challenge, particularly as the nature of the data collected is changing over time.

All these mixtures contain molecularly complex substances, and accurately predicting their VLE behaviour is a considerable challenge for molecular-based approaches, as well as for traditional engineering approaches.

Yet, the large scale of many sequencing projects and the sheer volume of sequence data create a considerable challenge for the individual investigator as well as consortia of researchers to obtain the resources and tools required to make maximal use of genomic information for comparative or functional studies.

That's a potent combination but it will still be a considerable challenge for loggly as it moves into this next dimension of its business.

Hence, this study could one day facilitate the identification of individuals at increased risk of recurrence, which remains a considerable challenge in the field [ 68], as well as personalized effective treatments.

It is a phenomenon described by other researchers [ 12] and poses a considerable challenge in maintaining Scotland as a first rate centre for general practice research and development.