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Hence, overall experimental uncertainty was reduced to a minimum, and measurements provide clear evidence that, for 28 of 59 investigated substances, over 85% of the pharmaceutical residue loads do not originate from the hospital when applying a conservative error estimation.
In our previous work on function evaluation or other arithmetic designs, we set a requirement of the absolute error of the whole calculation, and use a conservative error model to determine whether the current bit-width values meet the requirement or not [6].
We use a conservative error rate of α = 0.01.
In this respect, our method would result in undercounting of opposite-sex cells rather than overcounting, giving a conservative error.
As discussed earlier, we use a conservative error rate of α=1% and an average coverage of 1000× (i.e. r=1000).
This is a result of the adopted stringent typing procedure and represents a conservative error, which was resolved by following the typing protocol, i.e. cloning and sequencing of MHC in this individual.
Similar(52)
To sequence the same amount of data, but producing only two reads (i.e., forward and reverse) per locus, using traditional Sanger methods (assuming a very conservative error rate of 5%) at a cost of $2.50 per read (including cycle sequencing) the cost is $40,950.
Based on these observations, we made variant calls in the three natural viral samples using both 5×10-5 5×10-5more conservandve error rate of 5×10-4, where the formorerepresented the mean overall error rate and the latter approximated the Pconservativeerror
Second, the bounds must be reasonably sharp: an overly conservative error bound can yield inefficient approximations (N too large) or even dangerous suboptimal engineering results (unnecessary safety margins).
For the final paternity assignment, Cervus paternity simulations were run assuming a pool of 20 candidate fathers for each offspring (which we presumed to represent 95% of total possible candidate fathers), 95.7% of all loci typed, and a conservative genotyping error rate of 0.05 (the actual estimated genotyping error rate was less than 0.002).
The rather weak results obtained using the combined days might also be a result of the field modelling process, namely the rather conservative error budget and the use of no temporal and spatial damping.
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