The phrase "a consequential change in" is correct and usable in written English.
It can be used when discussing significant alterations or impacts in a particular context, such as policy, behavior, or conditions.
Example: "The new regulations will lead to a consequential change in the way businesses operate."
Alternatives: "a significant change in" or "a meaningful change in".
We asked as they were departing whether, with a new American President taking office, they anticipated any consequential change in Chinese-American relations.
For such a politically difficult task, the views of those most directly involved (e.g., those with cancer and family members) are needed to increase the chance of bringing about any consequential change in this area.
Rather than an abrupt departure, same-sex marriage is the culmination of a larger and ultimately more consequential change in the nature of marital relations between men and women.
In a Critic at Large that ran in 2004, Adam Haslett discussed how the debate over same-sex marriage illuminated already-existing changes in the traditional notion of matrimony: Rather than an abrupt departure, same-sex marriage is the culmination of a larger and ultimately more consequential change in the nature of marital relations between men and women.
Hence, the most consequential change in the biology of an infectious pathogen is when it makes the transition from a non-sustainable infection to a rapidly spreading infection when it crosses the threshold at R0 = 1.
At the end of the process, we identify a small subset of genes which exhibit disruption through multiple mechanisms and show consequential change in gene expression.
"It's the biggest and most consequential change in Amish life since they came to North America," Kraybill said.
It now seems more likely that, rather than being plunged back into a medieval deep-freeze, consequential changes in the Gulf Stream will merely slow the warming of Europe.
