Sentence examples for a consequential activation of from inspiring English sources

The expression of genes encoding for ICAM-1 and TNF-α is controlled by the nuclear factor NF-κB. Site-specific phosphorylation of the inhibitor IκB leads to its degradation by proteasome and to a consequential activation of the NF-κB pathway.

Thus, disruption to one element of the MAPK signalling network may conceivably cause consequential activation of other components.

In ruffles, IκBα can be degraded with consequential activation of NFκB [ 103].

KRAS mutation and the consequential activation of the MAPK kinase axis are regarded as major driving forces of PDAC progression.

However, the presence of NHERF1 and consequential activation of the PKC pathway are important for normal bone growth, as NHERF1 null mice showed a reduction in the rate of bone reabsorption as well as bone formation, resulting in bone that is 25% weaker because of a lack of collagen cross-linking.

It has been advocated that ASCL1 expression may favour cancer cell growth through repression of DKK1 with the consequential aberrant activation of the Wnt/β-catenin signalling pathway [ 9].

reported a PCR validation rate of 1/96 and a consequential paucity of L1 activity.

Genetic drift is therefore considered to be a consequential mechanism of evolutionary change primarily within small, isolated populations.

Mitochondrial dysfunction can be either a causal or a consequential event of abnormal signaling in specific brain circuitries.

There is also a consequential impact of alcohol availability on health services [ 18- 20].

Flour almost always burns on, so a consequential removal of burnt residue is virtually unavoidable.