Sentence examples for a consequent reduced from inspiring English sources

Accumulation of storage material presumably arises from lysosomal deficiency and a consequent reduced autophagic turnover, thereby giving rise to increased autophagosome accumulation (53, 63).

As IFN-α can cause an alteration of the tryptophan metabolism and a consequent reduced synthesis of serotonin, we have designed a study aimed to investigate the effect of IFN-α therapy on the serum levels of tryptophan and on the development of depression in patients affected by the hepatitis C virus.

Decreased use of headache analgesics during pregnancy may be explained either by an improvement in headache with a consequent reduced need for analgesics, or by a reduction in analgesics intake despite pain due to fear of foetal damage or based on direct advice from others.

The results of this study suggest that adverse plantar pressure patterns are associated with redistribution of joint moments, and a consequent reduced capacity to control forward velocity at heel strike.

When injected into the animal glioma model, MSC PEDF might be integrated into the host vessels and thus decreased the angiogenesis, with a consequent reduced blood supply, which was pivotal to glioma growth and metastasis.

This finding could be explained by the fact that in patients with diabetes, PPAR receptors are more phosphorylated with a consequent reduced transcriptional activity, 34 35 and the balance between PPARγ expression and activity levels is altered.

Osteoporotic vertebral fractures are a major health care problem; they cause severe, debilitating back pain and consequent reduced physical function and have an enormous impact on quality of life [ 1].

Many causes bring to higher temperatures in urbanized environment, such as anthropogenic heat, excess of heat stored by construction materials, decreased long-wave radiation losses from urban areas, lack of vegetation and reduced evapo-transpiration processes, reduction of wind speed and consequent reduced convective heat removal from urban surfaces to the atmosphere.

These findings suggest a compensatory change caused by increased LH stimulation of the Leydig cells (de Kretser 2004; Ochsenkuhn and de Kretser 2003), a change that probably results from initial suppression of steroidogenesis with consequent reduced negative feedback to the hypothalamus pituitary unit.

Yet, Nav1.5 inhibition and consequent reduced Na+ entry might also increase forward-mode NCX activity (Liu et al. 2011, Sikkel et al. 2013), thus reducing diastolic Ca2+.

In contrast, a mouse model of X-linked hypophosphatemia with deficient Wnt coreceptor low-density lipoprotein receptor-related protein 6 and consequent reduced Wnt signaling did not alter FGF23-induced phosphaturia or reduced mineralization of the bone, suggesting a potential Wnt-independent pathway of phosphate homeostasis.