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Refugees are particularly vulnerable to infections as a consequence of undernutrition, unclean water, poor sanitation, over-crowding and limited access to health care.
In low-income settings, however, weight faltering is more often a consequence of undernutrition, with good evidence to suggest poorer psychological and cognitive outcomes and a greater need for intervention.
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This represents some 4.5 million people of working age who are not able to achieve their potential as a consequence of child undernutrition.
Early life growth restriction discussed here refers to decreased body weight compared to normal birth weight peers, which is commonly observed as a consequence of maternal undernutrition or conditions such as preeclampsia and other forms of placental dysfunction whereby sufficient nutrient supply fails to reach the fetus.
Figure 2A shows that while UN/Sal pups are severely growth restricted in utero as a consequence of the maternal undernutrition, AD/Lep pups also show a significant restriction in neonatal growth rate during the period of treatment (see Additional file 4: Table S4 for raw data).
The scant oral intake, as a consequence of his disability, caused progressive undernutrition which closed a vicious circle, delaying his development and his ability to overcome the swallowing handicap.
Despite the concerns of many physicians, it is known that no other species, except humans, are evolutionarily adapted to chronic undernutrition as a consequence of ecologically dictated dietary restrictions [ 32].
It is likely that the epigenetic effects of undernutrition will vary geographically, both as a consequence of varying conditions in the environment and the genetic and epigenetic history of the affected populations.
Given the likely long-term negative consequences of undernutrition and infection during a child's first years, the global development community would benefit from rigorous evidence about the effects of single and combined WASH and nutritional interventions on child illness and growth.
Conclusions Our data suggest that early postnatal high-energy nutrient intake for SGA preterm infants is needed to promote HC catch-up growth and to prevent negative consequences of undernutrition.
For infants and children under the age of two, the consequences of undernutrition are particularly severe, often irreversible, and reach far into the future.
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