Sentence examples for a consequence of targeted from inspiring English sources

The development of obstruction in the proximal epididymis as a consequence of targeted Ar deletion provides strong evidence for a direct role of androgens in the regulation of this epididymal zone.

"So many of them have been killed in the last one to one and a half years as a consequence of targeted assassinations," he said in an interview.

Inhibition of nucleic acid synthesis can also occur as a consequence of targeting other metabolic pathways.

Another advantage is increased levels of phylogenetic information in target regions, compared to those targeted in UCE studies (A.R. Lemmon, unpub. data), as a consequence of targeting more variable regions of the genome.

· Evidence of downstream pharmacodynamic effects as a consequence of target engagement.

As a consequence of target inhibition, a marked proportional decrease of monocytes has also been previously reported by other investigators [ 4].

Apparent dual localization to rhoptries and micronemes has previously been reported by others [19], [22], although in all cases (including this report) it is unclear whether the native protein is targeted to both organelles (alternatively, this could be a consequence of inefficient targeting due to recombinant engineering of fusion proteins under the control of heterologous promoters [51]).

While some of these deletions may be a consequence of LOH targeting the nearby TP53 gene on 17q12, in a few instances there are homozygous deletions that appear to target only MAP2K4.

As a consequence of selective targeting of a minor subpopulation of cells, in conjunction with the short range of the alpha particles, no discernible toxicity was seen in therapy studies with 225Ac-E4G10.

pRb can also be indirectly inactivated in other tumor types as a consequence of alterations targeting genes coding for any of its several upstream regulators such as CDK4, cyclin D and p16ink4a [6].

Indeed, it has been postulated that the observed synergisms of this RNase may be a consequence of onconase targeting specifically the family of microRNA shown to enhance tumor resistance to cytotoxic anticancer therapy by mobilizing the cell defense mechanisms [ 6].