The slight inhibition of IL-10 by elevation of cAMP is thought to be a consequence of the potent inhibition of TNF-α.
The overall resistance of the skeleton to T4 treatment in Thra1 PV /+ mice and the patients studied so far is likely to be a consequence of the potent dominant-negative activities of their mutant TRα1 proteins (5 – 7, 14, 18).
The formation of these microparticles is considered to be a consequence of platelet activation with potent agonists, which indeed give rise to massive shedding of 'activation-induced' microparticles with a strong procoagulant potential in vitro.
Both L-carnitine and fenofibrate are inducers of CrAT transcripts, but the important hyperlipidemic drug fenofibrate being a more potent one, as a consequence of its pharmacological interaction.
A thorough understanding of this family of proteins would generate a tremendous knowledge base for discovering and predicting protein interactions, for designing highly specific and potent inhibitors, and, as a consequence of these facts, for understanding the cell and disease.
Residents, especially children, likely suffered irreversible brain damage as a consequence of needlessly being exposed to elevated levels of lead, a potent neurotoxin.
Loss of GFP fluorescence was apparent in cells that had received the most potent proapoptotic combination of drugs (PSI/VPA/salubrinal), possibly as a consequence of the partial loss of reporter cells due to extensive cell death.
The reduction in conjugation was not a consequence of increased proteasome activity since the conjugates also decreased after treatment of the cells with MG115, a potent proteasome inhibitor (Figure 5E).
"Making together a consequence of America".
Beriberi is a consequence of thiamine deficiency.
