Most types of centromere are not defined by their DNA sequence [ 8], so a trivial explanation is that their rapid evolution is simply a consequence of low levels of selective constraint.
KS patients are described as hypergonadotropic hypogonadal subjects with invariably high LH and FSH serum levels as a consequence of low levels of circulating testosterone and inhibin B, produced by LCs and SCs, respectively [ 23].
The defect we observe in the repair of DSBs might be due to an impairment of RNR activity as a consequence of low levels of NADPH and to an imbalance in the dNTPs pool, whose de novo synthesis depends on the PPP and RNR.
Based on the results presented in this article, cellular heterogeneity of multi-lineage priming may, therefore, be hardwired into HSPC regulatory networks rather than being a consequence of low-level, non-specific gene expression noise as had been speculated previously.
The large mismatch between collagen's lifetime in the third channel is possibly a result of the sensitivity of lifetime estimation to SNR which is a consequence of low signal level in collagen's spectro-temporal profile in the third channel.
Plasma apoM and S1P correlate positively, suggesting that sepsis patients could have decreased plasma levels of S1P as a consequence of low apoM levels; however, no reports on plasma levels of S1P in sepsis patients have so far been published.
On the other hand, productivity growth has shown to be latent in almost all analyzed countries, which might be a consequence to low level of technological advance and less endogenous development.
Thus the lack of toxicity of cytoplasmic CUG foci does not appear to be a consequence of low expression levels.
However, reduced snRNP assembly capacity in vitro as a consequence of low SMN levels may not necessarily translate into a defect of snRNP synthesis in vivo if the SMN complexes are in excess.
In addition, ARDS could be a cause rather than a consequence of low substrate levels.
We concluded that our results with Dlx1 and Dlx2 probes were not due to experiment or probe artefact, but most likely were a consequence of low expression levels for these two genes during caudal primary scale development.
