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In OA, most authors have focused their studies on joint architecture and local degradation, considering pain as only a symptom, a consequence of joint damage.
Surgical models of OA can also induce histological and behavioural alterations as a consequence of joint instability [ 7, 8, 54].
It is likely that altered pain processing may both contribute to and be a consequence of joint pathology.
Joint capsules are dynamic tissues, stretching and relaxing as a consequence of joint movement and mechanical stimulation appears essential for maintaining capsule elasticity.
The collagenase model combines the advantage of inducing OA as a consequence of joint instability and degradation of collagen in the articular cartilage, with the methodologically simple i.a.a
In addition, due to the aged less activity, the declined quadriceps strength may be another factor responsible for altered joint loading patterns as a consequence of joint laxity [ 80].
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Power may be limited with this approach, due to some joint effects having low representation; however, this is not a limitation of the method but rather a consequence of exploring joint effects that occur infrequently.
The second makes use of the direct analog of an argument of Tropp [41] proving the concavity in Y of (mathrm{Tr}[e^{ H+ log Y}] = Psi (H,Y) + mathrm{Tr}[ Y] as a consequence of the joint convexity of the Umegaki relative entropy.
Making the change of variables (Z = W^{1/2}e^HW^{1/2}) in (1.18), one sees that the supremum in (1.20) is exactly the same as the supremum in (1.21), and thus for all density matrices X and W, (D_D(X||W) le D(X||W)) which can also be seen as a consequence of the joint convexity of the Umegaki relative entropy.
During this stage (pillow stage), salt movement occurred due to buoyancy effects at the depressive and tectonically weak loops (Fig. 6), while in the compression stage (Cr2-Serravalian) (diapir stage), the Berati anticlinal belt development, was a consequence of the joint action of tangential forces and the contribution of salt tectonics.
Contractures are prevalent clinically as a consequence of casting, joint arthroplasty, sports injuries, bed rest and others [ 2– 6].
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