The phrase "a consequence of germ" is not correct and does not convey a clear meaning in written English.
It may be intended to refer to an effect or result related to germs, but it lacks clarity and context.
Example: "The outbreak was a consequence of germ transmission in crowded areas."
Alternatives: "an effect of germs" or "a result of germ exposure".
RBR-2 did not play a comparable role in the maintenance of quiescent germ cells in dauer larvae, implying that it represses stress that occurs as a consequence of germ cell proliferation, rather than stress that accumulates in nondividing cells.
These observations suggest that in analogy to cellular DNA damage checkpoints that allow time for DNA repair, the somatic stress resistance might function as systemic DNA damage checkpoint that preserves somatic functions when offspring generation is delayed as a consequence of germ cell DNA damage.
This suggests that these features are typical of under-stimulation by commensals and that they are reversible effects rather than a consequence of growing up germ free.
A similar picture can be depicted for down-regulated genes, among which we identified only few transcripts expressed in germinal epithelium, and thus under-expressed as a consequence of the lack of germ cells, and a larger number of transcripts whose under-regulation was the result of the alteration of the SCs and LCs transcriptome.
The overall depletion of CpGs throughout the genome is thought to be a consequence of the methylation of some germ-line CpGs and their susceptibility to mutation.
CLU is synthesized by SCs and regulates the germ cells proliferation and differentiation and its down-expression could be the consequence of germ cells absence.
We postulate that both morphological changes are a consequence of abnormal spindle orientation within dividing germ line stem cells.
These findings and the early morphological changes in the Sertoli cells produced by DPP suggest that phthalate esters may act initially to cause Sertoli cell injury, the subsequent loss of germ cells occurring as a consequence of this.
The lack of germ cell disruption in any of the fish examined in the ELS study or in effluent-exposed adult males derived from estrogen-free environments indicated that either the estrogenic potency of effluents tested was not sufficient to induce this feature of feminization, or that germ cell disruption is a consequence of a longer term exposure to treated wastewater effluent.
A major obstacle that had to be overcome was to identify transcriptional regulation resulting from the 'deletion effect' and not from the dominating effect of altered germ cell composition as a consequence of YCMD (Ferras et al. 2004), herein termed as 'germ cell effect'.
It is also likely that round cells observed in the lumen of flutamide-exposed males may derive from the testes, since a drastic decrease in testicular germ cell population was observed as a consequence of flutamide action (unpublished data).
