The phrase "a consequence of defective" is correct and usable in written English.
It can be used when discussing the results or outcomes that arise from something being defective or faulty.
Example: "The product recall was a consequence of defective manufacturing processes that compromised safety."
Alternatives: "result of faulty" or "outcome of flawed".
We investigated if the impairment in GC formation associated with PMIF was a consequence of defective Tfh differentiation.
We hypothesized that the severe developmental and neurological problems in CS may be a consequence of defective processing of endogenous oxidative DNA lesions.
Regarding its biological characterization, yet another caveat lies in the fact that reduced uric acid levels may be found in patients with presumed CSW, similar to SIADH, perhaps as a consequence of defective tubular reabsorption of uric acid [213, 215].
Whether or not this is a consequence of defective cell adhesion and migration remains unclear.
Axonal clogs are aggregates of membrane bound cargoes and can be a consequence of defective axonal transport [36].
In addition to these observations we have recently described a major defect in the innate immune response of CD patients in response to bacterial stimulation, which results in impaired clearance as a consequence of defective cytokine secretion from macrophages[5].
Mitochondrial enlargement can be a consequence of (1) defective fission, (2) a high rate of fusion and (3) impaired mitophagy.
As a consequence of their defective MMR, HNPCC/LS tumors and sporadic CRCs display increased rates of replication errors at short repeat sequences, termed microsatellite instability (MSI).
Detailed analysis of CSPα-deficient mice has shown that neurodegeneration in the absence of CSPα is a consequence of the defective function of SNAP-25 and SNARE binding proteins [ 14].
At basal cAMP levels, wild-type DISC1 inhibits the transcriptional activity of ATF4, an effect that is weakened by both 37W and 607F independently, most likely as a consequence of their defective nuclear targeting.
We propose that the accumulation of 4N DNA content following ICL-inducing agents in FA cells (57) is a consequence of both defective DNA repair and a failure in recovering from checkpoint arrest through the inhibition of CHK1.
