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As a consequence of cancer expansion, cellular and molecular homeostasis of bone microenvironments is disturbed and bone is destroyed, leading to the development of bone metastases.
Whether "Fusobacterium causes cancer, is an innocent bystander or is a consequence of cancer, there are obviously more questions than answers," said Matthew Meyerson, HMS professor of pathology Dana-Farmer Cancer Institute.
This argues that lower levels of magnesium (or high calcium/magnesium ratio) are not simply a consequence of cancer, but does not remove the possibility that high-grade cancer in some way affects blood Mg levels.
Criterion C: the fatigue symptoms are a consequence of cancer or cancer therapy.
Other important questions to ask relate to whether or not the individual hallmarks are a cause or a consequence of cancer development?
Therefore, global hypomethylation may be one of the mechanisms that promote carcinogenesis and is unlikely to be just a consequence of cancer development.
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In the context of ovarian cancer, it is not clear whether the components of glycomic profiles published in the literature are unique to this cancer or, alternatively, are a consequence of cancer-related metabolic defect(s).
Because of the established T cell dysfunction as a consequence of cancer-mediated immunosuppression, our data strongly suggest that T cell-based therapies could significantly benefit from modulation of this NR2F6 inhibitory signaling pathway.
Muscle wasting is frequently a consequence of cancers, AIDS, immobilization and fasting [ 1].
The observed association may reflect pancreatitis as an initiator of pancreatic cancer and/or a consequence of pancreatic cancer.
Research is needed to assess misdiagnosis and the magnitude of its effect upon risk factor analysis and to determine whether pancreatitis is an initiating step for pancreatic cancer or a consequence of pancreatic cancer.
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CEO of Professional Science Editing for Scientists @ prosciediting.com