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Genetic ablation of the neurons expressing prothoracicotropic hormone (PTTH) delay pupariation and metamorphosis as a consequence of attenuation of ecdysone biosynthetic gene transcription [19].
Meanwhile, reduction in total PRs expression may be a consequence of attenuation ERα signaling, which is a key regulator of PRs expression.
It has been suggested that the age-related decline in Vo2max is a consequence of attenuation of central and peripheral functions such as stroke volume, heart rate max (HRmax), peripheral O2 extraction, and lean body mass (LBM) or muscle mass [ 19, 21- 25].
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This is probably a consequence of the attenuation of visual signals, in particular eye gaze, which has been shown to be important in impression formation.
This suggests that the reduction in expression of early differentiation genes could be a consequence of an attenuation of the FGF pathway by PRDM14.
It is possible that the increased radiation sensitivity is simply a consequence of the attenuation of IR-induced G2/M arrest by Rac1 inhibition.
DOI: http://dx.doi.org/10.7554/eLife.04872.012 Induction of PPP1R15A was observed in thapsigargin-treated cells from 2 hr onwards but was diminished in cells co-treated with jasplakinolide (likely, a consequence of profound attenuation of protein synthesis).
Thus, the highly specific growth and gene expression phenotype observed in wild type cells is a consequence of expression site attenuation, which does not occur in the DOT1B knockout cells.
The observation that vorinostat downregulates TS protein expression both in vitro and in vivo as a consequence of vorinostat-induced attenuation of TS mRNA transcript confirmed previous findings from our group and from others (Glaser et al, 2003; Lee et al, 2006; Tumber et al, 2007; Di Gennaro et al, 2009; Fazzone et al, 2009).
The consequence of attenuation is a reduction in the number of gamma photons which can arrive directly at the detectors, caused by photon scattering and absorption.
Hiatal shell concentrations, which formed as a consequence of landward and seaward stratal attenuation, are associated with sequence bounding and intrasequence surfaces.
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