These results were very clear-cut and presumably are a consequence of altered Sse1 function due to the structural alterations.
Furthermore, differences in pericyte loss and vasoregression are more likely a consequence of altered glucose-driven pathways than of insulin signaling alterations [ 18].
Although preliminary evidence suggests alterations in gut microbiota in patients with IBS, it remains to be determined if these alterations are a cause or a consequence of altered gut motility and secretion.
In summary, the experiments confirmed that the tumor associated alternative TSS usages observed for TCF12, OSBPL1A and TRAK1 were indeed due to altered expression in the carcinoma cells, and not a consequence of altered tissue composition.
Human pancreatic cancer cells may exhibit loss of responsiveness to TGF-β-mediated growth inhibition as a consequence of altered TGF-β expression as well as a result of postreceptor alterations [ 10].
Conversely, alterations in osteoblastogenesis and bone metabolism have been reported as a consequence of altered lamin A/C levels in vitro and in vivo [ 55- 57].
This may be a consequence of altered glycogen metabolism and inhibition of peripheral glucose uptake through Glut4 [26].
Characteristic changes in the mobile chain end fraction with temperature, in particular its decrease with increasing degree of filling are interpreted as a consequence of altered contour-length fluctuations.
Purkinje neurons and their dendrites, which were not targeted by Cre-mediated recombination of Fgf receptors, were also misplaced in FGFR DKO mice, possibly as a consequence of altered Bergmann glia orientation or reduced granule cell number.
This difference is explained by their CNS-linked hyperactivity and is not a consequence of altered food intake [11].
Alternatively, it might be a consequence of altered fibronectin matrix assembly, as has been observed in fibroblasts [17].
