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The G4 sequences either consisted of 4 stretches of several guanines separated by single adenines or of a consecutive stretch of Gs.
Alignments are extended at candidate loci, requiring that the read has a consecutive stretch of 14 nucleotides exactly matching the reference sequence.
More formally, let A yield { I 1, …, I m } insertion blocks, where any I k represents a consecutive stretch of coordinates that are inserted in T (with respect to S).
Our program can detect splicing, multiple mismatches, long indels and combinations thereof, up to a user-specified point total, limited to a single splice or indel per read, provided the read (or parts of the read on each end of the indel or splice) has a consecutive stretch of 14 nt that match the reference sequence (Fig. 1A).
In our analysis, we defined a minimum repetitive stretch of 10 nucleotides as mono-nucleotide, a consecutive stretch of 4 repeats units to be classified as di- and tri-nucleotide, and a stretch of 3 repeat units for each tetra-, penta- and hexa-nucleotide stretches as simple sequence repeats (SSRs).
It is likely that these longer mRNAs are less stable, which is supported by the increased appearance of degradation products in the RP analysis as seen in Figure 2C and D. From these results we concluded that, in the context of the MC4R poly(A) signal, a strong DSE and a consecutive stretch of adenosines are sufficient to direct efficient 3′end cleavage.
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It is a short consecutive stretch of DNA that will be used in de bruijn graph as described elsewhere [ 20].
An initial x-ray open conformation of bulged-out bases in HIV-1 DIS complexes, affected by crystal packing, tends to convert to a closed conformation formed by consecutive stretch of four stacked purine bases.
That was a better-than-expected number and it continued the longest consecutive stretch of job growth on record.
Colour intensities refer to the length of the respective longest consecutive stretch of matches.
The longest consecutive stretch of identical amino acids in this region of ARR1 and ARR2 is six.
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