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For a confirmatory study with four to one pre-study odds, the chance that any positive effects are spurious is reduced to 25%.
Caclin, A., McAdams, S., Smith, B. K. & Winsberg, S. Acoustic correlates of timbre space dimensions: a confirmatory study using synthetic tones.
"Acoustic correlates of timbre space dimensions: a confirmatory study using synthetic tones". <i>The Journal of the Acoustical Society of America</i> 118(118471182.
"Acoustic correlates of timbre space dimensions: a confirmatory study using synthetic tones". The Journal of the Acoustical Society of America 118(118471182.
This was done in three clinical studies: a screening study, followed by a prediction study and, finally, a confirmatory study; in all 17 experimental formulations were investigated.
We describe a confirmatory study in 212 prostatic adenocarcinoma and 135 benign prostatic hypertrophy patients designed to determine whether previous findings showing a protective effect for UV exposure could be reproduced.
Similar(7)
Since then, there has been a single confirmatory study describing a novel homozygous frameshift mutation in one family [ Alessandri et al., 2010].
Another thing these studies have in common, however, is that they are all on relatively small samples of patients, and it is gratifying to see that Dwivedi et al. already have a grant to complete a larger confirmatory study.
A brief definition is that a pilot study is a 'small study for helping to design a further confirmatory study'[ 1].
In this study of low-moderate risk patients admitted to our CPU who underwent hs-CRP testing, we found little diagnostic utility for detection of ACS as defined by a positive confirmatory study or subsequent adverse cardiac event during a limited post-discharge interval.
Second, the study sample was small on one hand, and lacking a control group on the other, an issue which again emphasizes the need for a following confirmatory study.
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