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Even though this was a concrete hypothesis, there were still questions on the functionality of this pathway within mitochondria.
The weak sequence homologies outside the zinc-finger and WRKY domains with other plant genes make it difficult to establish a concrete hypothesis about the functions of their grape homologs other than to note that most showed mRNA expression in the skin.
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In order to show a more concrete hypothesis, we need to clarify what mechanisms (local rules) determine such structural properties, and need to reveal the relationship between the mechanisms and growth temperature.
We next investigate the correlation between the parameters and growth temperature, and present a more concrete hypothesis for the origin of structural differences in metabolic networks with respect to temperature.
For example, SNP rs1801274, which was previously associated with systemic lupus erythematosus, inflammatory bowel disease, and Crohn's disease, impacts FCGR2A/CD32 receptor expression in cis, as well as CD27 and CD161 expression on T cells, generating a novel and concrete hypothesis for how rs1801274 alters the immune system in humans.
Future studies focusing on the association between improving bowel health and reduction of COPD exacerbation may assist in forming more concrete hypothesis relating to how these two clinical entities inter-relate to one another.
Here, the concrete hypothesis suggested that phosphorylation events change the conformational status of tau molecules and leads to the decreased microtubule binding in turn leads to the instability of microtubules because of loss of microtubule assembly (Ishiguro et al., 1999).
It has been postulated that turtle scratching and swimming arise when "behavioral modules" interact and combine to control "muscle synergies" producing appropriately coordinated motor outputs [32], but there is a large gap between such an abstract statement and concrete hypotheses about the neuronal networks involved.
This context-specific model refinement provides concrete hypotheses: maybe a putative interaction shown in a yeast two-hybrid experiment does not occur in vivo, or maybe the transformed cell line phenotype is simply different from the canonical pathway.
This pattern of results represents a starting point for the formation of concrete hypotheses concerning the effects of atomoxetine on specific aspects of cognition in Parkinson's disease, to be directly investigated in future studies.
He suggested that hierarchy in language and music builds upon a more basic sequential action system, and provided several concrete hypotheses about the nature of this system.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com