Sentence examples for a concordant effect on from inspiring English sources

Yet, not all studies could link improvements in clinical outcome to a concordant effect on TNF-α modulation [ 116].

Thus, a treatment effect on TTP/PFS translated into a concordant effect on OS, but with attenuated effect size.

However, a concordant effect on mRNA and protein stimulation with both cytokines was demonstrated for the α isoform of IL-32.

Therefore, in the only study where divergent selection lines for mating system have been used in a mammal, sexual selection appears to confer a long-term fitness benefits to males and females, suggesting concordant effect on sexual and nonsexual traits.

Whether OI and DDIs result in concordant effects on drug pharmacokinetics is likely to be a function of a drug's elimination pathways and the effects of OI on metabolism and transport.

Most knockdowns also produced concordant effects on survival of hydrogen peroxide stress, which can trigger lipoperoxide chain reactions.

While we do not dispute this, our results nevertheless seem to indicate that most of the mutations we assayed had sexually concordant effects on adult fitness.

It also provides another illustration that incompatibility factors with concordant effects on the sexes induce lower barriers than expected under multiplicativity and factors with discordant effects induce higher barriers.

However, even if all mutations had concordant effects on fitness, the range in presented here (1.06-2.14) could be consistent with anything from modest benefits of sexual selection to females to a greater than two-fold fitness advantage compared to a hypothetical asexual competitor, depending on the mutation rate, so refining estimates for through further study will be critical.

The lead SNP for AMH protein levels (rs4807216) was also the same lead SNP for the strongest genome-wide signal for AMH mRNA levels (skeletal muscle, P = 1 × 10−15); however, for rs4807216 (and also rs8112524) the mRNA increasing allele was associated with decreased protein levels, despite directionally concordant effects on mRNA across all significant tissues.

Highly concordant effect estimates were observed in a GCTA joint model (Table 1), further highlighting the utility of this methodology.