The phrase "a concomitant attenuation of" is correct and usable in written English.
It can be used in contexts where you want to describe a simultaneous reduction or weakening of something alongside another event or condition.
Example: "The study found a concomitant attenuation of symptoms in patients receiving the new treatment."
Alternatives: "a simultaneous reduction of" or "an accompanying decrease in".
However, with increasing evolutionary age, we observed a significant increase in the frequency of both partial and chimeric duplicates as well as a concomitant attenuation of duplication spans.
AGE restriction normalized AGER1, SIRT1, and SIRT1-dependent NF-κB p65 deacetylation levels, and there was a concomitant attenuation of proinflammatory mediators (i.e., RAGE and TNF-α) (9).
We hypothesized that CYP2E1-mediated oxidative stress causes M1 polarization in experimental NASH, and that nitric oxide (NO) donor administration inhibits CYP2E1-mediated inflammation with concomitant attenuation of M1 polarization.
This was accompanied by increased apoptosis and concomitant attenuation of Notch-1 and NF-kappaB and down-regulation of NF-kappaB downstream genes, such as matrix metalloproteinase-9 and vascular endothelial growth factor, resulting in the inhibition of pancreatic cancer cell invasion through the Matrigel.
Proliferative index Ki67 was reduced in metastatic deposits of 2H6-treated mice only (Fig. 4f), and we noted concomitant attenuation of Notch target genes (Hes1, Hey1, Hey2, HeyL), as well as key mediators of metastasis, such as periostin, MMP7, MMP9 [ 14, 15] (Fig. 4g, h).
After application of APAP, mice lacking TNF-α receptor as well as mice treated with anti-TNF-α antibodies showed a reduction in the neutrophil response and a concomitant significant attenuation of liver damage [ 38, 39].
In addition, a decrease in TGM-2 activity has been reported to result in concomitant attenuation in cell adhesion [37], which may for example, facilitate migration of abnormal pterygium tissue towards the central cornea.
As a consequence of this process the virus becomes more adapted for the embryo, reflected by more efficient replication and higher pathogenicity for the embryo, with concomitant attenuation for chickens and in some cases loss of immunogenicity.
Taken together, we have demonstrated that, in GLO1 Tg rats, age-related acceleration in glycative and oxidative stress was mitigated and age-related endothelial dysfunction was ameliorated, concomitant with attenuation of age-related eNOS (Thr495) phosphorylation and eNOS (Ser1177) dephosphorylation, resulting in increased NO bioavailability and amelioration of endothelial dysfunction.
These effects might be associated with a concomitant inhibition of neutrophilic elastase and an attenuation of the normal rise in proinflammatory cytokines normally detected on the first postoperative day after cardiac surgery.
Phosphorylation of eIF2α leads to attenuation of general translation initiation, but also to a concomitant translational activation of selected proteins, including ATF4 [ 12], a homologue of S. cerevisiae Gcn4p.
