Sentence examples for a compromised checkpoint from inspiring English sources

Since the products of HPGI genes are involved in checkpoint controls of the cell cycle, we reasoned that the faster cycle time in the heterozygotes could be the result of cells skipping a compromised checkpoint and therefore progressing faster through that phase of the cycle.

Cell death results from the premature entry into mitosis because of a compromised G2/M checkpoint.

The reduced ability of mad2-S187D to bind Mad1p can explain its compromised checkpoint arrest, but why do S92 substitutions perturb checkpoint arrest?

In addition, we investigated several cell cycle-related proteins and found that co-knockdown of hTopBP1 and hMYH significantly diminished cell cycle arrest due to compromised checkpoint kinase 1 (Chk1) activation.

For this reason, a compromised mitotic spindle assembly checkpoint has an important function in chromosomal instability (CIN) (Yoon et al, 2002), characterised by accelerated rates of chromosomal aberration (Lengauer et al, 1998) and resultant aneuploidy (Lengauer et al, 1997).

Thieu was a compromised figure, tainted by defeat and scandal.

Despite a compromised economy, Americans are still making travel plans.

Another was looking specifically for a compromised America Online account.

He walked into the National Assembly with a crisis of credibility and as a compromised leader.

The result is a compromised film – a bewildering hybrid of Aki Kaurismäki and Roy "Chubby" Brown.

"I wanted a perfect title, I didn't want a compromised title.