Sentence examples for a comprehensive target from inspiring English sources

By providing a comprehensive target sequence file that accounts for all known polymorphisms within the alleles tested, we hypothesized that only reads having the legitimate base will be recruited and co-assemble with the appropriate target sequence.

For each miRNAs of interest, a comprehensive target prediction was obtained.

Recent studies using high-throughput methods have revealed that transposable elements (TEs) are a comprehensive target for DNA methylation.

A comprehensive, target driven lifestyle and pharmacological strategy improve their prognosis to be almost similar to that of patients without diabetes [ 6, 7].

Gene radA, Rv2165c, fadA, pgk, Rv3802c, and atpB are all annotated as potential targets in a comprehensive target identification pipeline including a network analysis of the protein-protein interactome, a flux balance analysis of the reactome, experimentally derived phenotype essentiality data, antibiotic resistance, sequence analyses and a structural assessment of targetability [ 55].

Even though there were many potential target genes predicted for the cloned miRNAs, several filtering and screening procedures (see materials and methods) have enabled us to generate a comprehensive target list consisting of 115 potential genes from all the predicted targets (Additional file 3).

Yet studies also tell us that the best chance for optimum results is to catch it early and initiate a comprehensive, targeted intervention specific to their needs.

In this review, we have compiled and discussed the biological potential of s-triazine derivatives, which could provide a low-height flying bird's eye view of the triazine derived compounds to a medicinal chemist, for a comprehensive and target oriented information for the development of clinically viable drugs.

A comprehensive approach targeting the assessment of the aforementioned rotorcraft design for civil applications is presented herein.

In this chapter, we review methods to evaluate and improve the DNA cleavage activity of programmable site-specific endonucleases and describe a procedure for a comprehensive off-target profiling method based on the in vitro selection of very large (~ 1012-membered) libraries of potential nuclease substrates.

These plans seek to develop a comprehensive method targeting all transport modes in urban areas [20].