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The phrase "a comprehensive clarification" is correct and usable in written English.
It can be used when you want to indicate that a detailed and thorough explanation is being provided.
Example: "In order to address the confusion surrounding the policy changes, we will provide a comprehensive clarification in the upcoming meeting."
Alternatives: "a thorough explanation" or "an in-depth clarification."
Exact(2)
A comprehensive clarification of the variables that influence airway function in this system will require not only the acquisition of an extensive set of functional data but also of additional data including mucous production, permeability and airway structural changes, i.e. remodeling.
Although such phenomena still lack a comprehensive clarification, epigenetic mechanisms are likely to be involved as epigenetic drugs could partially counteract MHC down-modulation in vivo.
Similar(58)
Müller, while proclaiming to be pursuing a "relentless and comprehensive clarification of events," has offered no insight to what went wrong.
"From the very start I have pushed hard for the relentless and comprehensive clarification of events," he declared.
He added: "Swift and comprehensive clarification has now utmost priority.
Its clarification will be beneficial to get a comprehensive understanding of the switching mechanisms.
Such a large number of definitions added more confusion than clarification to the discussion and led the group to the production of a comprehensive definition of the concept of multimorbidity with the help of a systematic review of literature [ 16].
(A comprehensive one).
I want a comprehensive deal.
"We conducted a comprehensive review.
This will provide a comprehensive overview".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com