Used and loved by millions
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com
a comprehensive alignment
Grammar usage guide and real-world examplesUSAGE SUMMARY
The phrase "a comprehensive alignment" is correct and usable in written English.
It can be used when discussing the thorough coordination or agreement between different elements, such as strategies, goals, or systems. Example: "The team worked diligently to achieve a comprehensive alignment of their objectives with the company's vision."
✓ Grammatically correct
Science
News & Media
Formal & Business
Alternative expressions(5)
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Human-verified examples from authoritative sources
Exact Expressions
2 human-written examples
Each STX gene query resulted in a comprehensive alignment that was submitted to a bootstrapped maximum-likelihood (ML) phylogenetic analysis [12], [13].
Science
Starting from a comprehensive alignment of genomic regions, Zhao and co-workers from the EFI have identified the epimerase activity, pathway context and biological role in osmoprotection of a structurally characterised enzyme of unknown function from P. bermudensis using a combination of virtual screening, metabolomics, transcriptomics and biochemical experiments [ 25 ].
Human-verified similar examples from authoritative sources
Similar Expressions
58 human-written examples
(A more comprehensive alignment, including several typical plant SKP1-like proteins, is shown in [ Additional Figure 2].) Only two amino acids, not among the key residues predicted to be involved in binding an F-box domain (Huang et al. 2006), are different between PiSSK1 and PhSSK1, suggesting that an SSK1 orthologue is present in P. inflata.
Science
A more comprehensive alignment is presented in the Supplementary Information and Guillemin et al. To obtain soluble stable recombinant human Bcl-B (Uniprot: Q9HD36) protein from E. coli fermentations for our structural studies, we mutated the cysteines 20 and 128 to serine and deleted 27 C-terminal residues in the predicted TM region.
Science
Implementing a center-wide precision medicine strategy at a major cancer center is a true multidisciplinary effort and requires comprehensive alignment of a broad screening strategy with a clinical research enterprise that can use these data to accelerate development of new treatments.
Science
The methylation output discriminates between sequence context (CpG, CHG or CHH) and can be obtained in either a comprehensive (all alignment strands merged) or alignment strand-specific format.
Science
These alignments and predictions were used to generate a comprehensive structural alignment of the HEPN domain superfamily, guided by secondary structure predictions, the results of the profile-profile searches with HHpred, and structural alignments generated by the DALIlite program.
Science
A multiple alignment of 1000 distinct S-helix representatives detected in our searches from across the three superkingdoms of Life were used to construct a comprehensive multiple alignment (Fig. 2; see additional file 1 for complete alignment) and a sequence logo quantifying the conservation at each position was derived from this alignment (Fig 3) [ 39].
Science
A comprehensive multiple alignment for the SLBB superfamily was prepared by combining alignments for individual groups constructed using the T-Coffee program, based on the structural superposition of transcobalamin C-terminal domain (2bbc) and Nqo1 middle domain (2fug; chain S).
Science
The on-line available RNAiSelect program (http://www.RNAiSelect.info/) was written in C .NET and performs a comprehensive sequence alignment against the input genome for up to 3 mismatches.
Science
In order to identify conserved protein signatures possibly participating in SPL7 function, we carried out a comprehensive multiple alignment among SPL7 and orthologs from different species including di- and monocots, a gymnosperm, a bryophyte and green algae.
Science
Expert writing Tips
Best practice
When using "a comprehensive alignment", ensure that you are referring to a deep and thorough agreement that covers all relevant aspects of the subject matter.
Common error
Avoid using "a comprehensive alignment" if the agreement only covers some aspects. Ensure the alignment truly encompasses all relevant elements; otherwise, it's more accurate to use terms like 'partial' or 'initial alignment'.
Source & Trust
81%
Authority and reliability
4.4/5
Expert rating
Real-world application tested
Linguistic Context
The phrase "a comprehensive alignment" functions as a noun phrase where the adjective "comprehensive" modifies the noun "alignment". It indicates a thorough and complete agreement or coordination between elements. Ludwig AI confirms that this phrase is correct and usable in written English.
Frequent in
Science
60%
News & Media
20%
Formal & Business
20%
Less common in
Encyclopedias
0%
Wiki
0%
Reference
0%
Ludwig's WRAP-UP
In summary, "a comprehensive alignment" is a grammatically sound and semantically rich phrase that indicates a thorough and complete agreement or coordination. Ludwig's analysis highlights its prevalence in scientific and formal contexts, suggesting a need for careful and complete coordination. While less common in informal settings, its precise meaning makes it valuable in academic, business, and news contexts. The alternative phrases provided offer nuanced ways to express similar concepts, and the writing guidance ensures its accurate and effective use.
More alternative expressions(6)
Phrases that express similar concepts, ordered by semantic similarity:
a unified agreement
Stresses the achievement of consensus in a consolidated manner.
a thorough integration
Emphasizes the process of combining elements into a unified whole comprehensively.
a complete reconciliation
Replaces alignment with a focus on resolving differences for a thorough agreement.
an exhaustive coordination
Focuses on the meticulous effort to ensure everything is aligned.
a full harmonization
Highlights achieving agreement and consistency across all aspects.
a well-rounded consensus
Highlights that an agreement is thoroughly discussed and complete from all point of views.
a total convergence
Implies elements coming together to a single point comprehensively.
a strategic alliance
Emphasizes a collaborative partnership based on aligned goals and benefits.
a detailed synchronization
Focuses on the precise timing and arrangement of elements working together comprehensively.
a holistic approach
Shifts from alignment to a comprehensive perspective that considers all aspects of a situation or problem.
FAQs
How is "a comprehensive alignment" used in academic writing?
In academic writing, "a comprehensive alignment" often refers to a thorough agreement between theories, methodologies, or research findings. It suggests a robust and well-supported connection between different elements of study.
What are some alternatives to using "a comprehensive alignment" in business contexts?
In business, consider using phrases like "strategic alliance", "unified agreement", or "thorough integration" to convey similar meanings depending on the specific context.
Is "a comprehensive alignment" suitable for informal communication?
While grammatically correct, "a comprehensive alignment" leans towards formal usage. In informal contexts, simpler terms like "full agreement" or "total match" may be more appropriate.
How does "a comprehensive alignment" differ from "a partial alignment"?
"A comprehensive alignment" indicates a thorough and complete agreement across all relevant areas, whereas "a partial alignment" suggests agreement exists only on some aspects, leaving other areas unaligned.
Editing plus AI, all in one place.
Stop switching between tools. Your AI writing partner for everything—polishing proposals, crafting emails, finding the right tone.
Table of contents
Usage summary
Human-verified examples
Expert writing tips
Linguistic context
Ludwig's wrap-up
Alternative expressions
FAQs
Source & Trust
81%
Authority and reliability
4.4/5
Expert rating
Real-world application tested