All assays were run in sequences that include 10 samples, authentic reference standard mixtures of 80 known compounds, pools of all samples and duplicate preparations of the same sample.
A sphere exclusion (SE) algorithm was utilized to randomly sample 'presumed inactive' compounds from a pool of ChEMBL compounds using a dissimilarity radius from known actives.
PDT-treatment of tumor cells, using the metal oxide nanoparticles, results in the cell death, presenting the consequence of irreversible DNA damage [146], plasma membrane disintegration [183], intracellular Ca2+ homeostasis disruption [179, 180], strong reduction or complete exhaustion of the redox compound pool, essential in ATP synthesis [184].
For each colony, we identified the cuticular compounds from a pool of 50 ants using full ion scans.
By the late 1980s, a series of battlefield setbacks were compounded by a smaller pool of volunteers, which undercut Iran's strategy of utilizing manpower to overcome Iraq's technological superiority.
Corroborative studies with a larger pool of compounds, refined network parameters and an improved modelling approach would be warranted in further investigations.
In this screening platform, three different yeast pools were interrogated with a single TAG4 array: a homozygous deletion pool, a heterozygous deletion pool, and a pool of genomic library transformants, each treated with a compound of interest.
In theory, this protocol could make a large pool of trifluoroethylated compounds accessible for the straightforward development of PET radiotracers [ 22, 50, 51].
(131) The intermediate stage of the Maillard reaction and related reactions provides a complex pool of reactive compounds, which are subjected to rearrangements and further reactions producing several classes of heterocyclic (volatile) products, several of which are important for cooked flavor.
Bioactive compounds comprise an excellent pool of molecules for the production of nutraceuticals, functional foods, and food additives (Joana Gil-Chávet et al. 2013).
