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Figure 3 Cirsimirtin (C 17 H 14 O 6 ), a compound identified through dereplication using experimental 13 C chemical shifts.
Figure 5 CID 9843671 (C 17 H 14 O 6 ), a compound identified through dereplication using experimental 13 C chemical shifts.
Figure 7 Ginkgolide A (C 20 H 24 O 9 ), a compound identified through dereplication using experimental 13 C chemical shifts.
Figure 4 8-epi-chromazonarol (C 21 H 30 O 2 ), a compound identified through dereplication using experimental 13 C chemical shifts.
Chemical shift differences greater than 2 ppm are highlighted in red. Figure 6 C 45 H 68 N 5 O 9, a compound identified through dereplication using experimental 13 C chemical shifts.
Interestingly, two of the glycosylated lipids we identified are tri-hexosylated sphingolipids that bear resemblance to iGb3, a compound identified as a major self antigen for murine NKT cells [21].
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42 Obatoclax was developed from a lead compound identified in a functional screen of natural compounds that detected disruption of protein protein interactions between members of the BCL-2 family.
Artemisinin (Qinghaosu), a natural compound identified in Artemisia annua L., is an effective drug mainly used against cerebral malaria.
A nitrogenous compound identified as 4- diethylamino)salicylaldehyde was found in treatment PGPB exudates on day 21, but not on days 7 and 14- diethylamino
Starting from a known compound, identified as the first inhibitor of the kinesin MKLP-2 and named Paprotrain, we have investigated its reactivity to produce through photochemistry a potent nanomolar inhibitor of the kinase DYRK1A.
In the present study, ENERGI-F704, a proprietary compound identified from bamboo shoots extract, exerts AMPK activation activity in human microglial cell model BV2.
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