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In spite of the conceptual limitations, "localizing" models are still the main approach to the identification of pathological changes as a component of the networks' structural and functional abnormalities [ 81].
Meanwhile, the BLA shows increased connectivity with the dACC, a component of the salience network.
Prat, T. et al. WRKY23 is a component of the transcriptional network mediating auxin feedback on PIN polarity.
Therefore CK is also a component of the regulatory network governing root development [ 23].
OPA1 is a component of the mitochondrial network and is involved in the positive regulation of anti-apoptosis.
The bone marrow of 46 patients with primary gastric cancer was examined for tumour cells, using immunocytochemical techniques and antibody reacting with cytokeratin, a component of the intracytoplasmic network of intermediate filaments.
Moreover, a methodological application of the concept in the area of Systems Biology is presented: a model for the production of antibiotic as a component of the stress response network for the bacterium Bacillus subtilis is described.
CRTR-1 has also recently been identified as a component of the complex transcriptional network that maintains pluripotency in embryonic stem (ES) cells.
This suggests that it can be a component of the gene regulatory network directly controlled by CRL1.
Our study suggests that lncRNAs may also be a component of the p53-regulatory network, similar to protein-coding genes.
miR-34a was demonstrated to be a direct transcriptional target of p53, and a component of the p53 transcriptional network [ 29- 31].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com