Sentence examples for a component of the class from inspiring English sources

Interestingly, expression of beclin-1, a component of the Class III PI3K complex that participates in autophagosome formation (45) was increased in MLIV fibroblasts (Fig.  2C and D).

To exclude the possibility that CQ and 3-MA themselves may have functions other than inactivating autophagosomes, we adopted siRNA of Beclin1, which targets a component of the class III PI3 kinase complex that nucleates autophagosomes.

Moreover, induction of autophagy was identified by two well-established measurements of autophagy, that is, enhancement of Beclin-1, a component of the class III phosphatidylinositol 3-kinase complessentialial for autophagosome formation, and degradation of p62, a protein facilitating autophagic degradation of ubiquitinated protein aggregation.

A similar model has been proposed to explain a block in trafficking induced by overexpression of Vps18, a component of the mammalian Class C Vps/HOPS complex that interacts physically with TSG101 [24].

As with any toolkit, users are able to use any component of the ClASS framework to meet their specific needs.

HLA-DRB3 is a component of the major histocompatibility complex class II and is essential in presenting bacterial antigen to CD4-positive lymphocytes.

Interestingly, our candidate list included one of six homologues of the SIN3-like (SNL) protein, SNL5, a component of the SIN3 complex that includes class I HDACs, e.g., HAD6/HDA19.

Possible differentiation of Th1 was indicated with changes of the transcript levels of IL-12β and beta-2-microglobulin-2 JB1 (B2M), a component of the major histocompatibility complex (MHC) class I (Fig. 2G, E).

Additionally, among the transcripts with functions involved in the adaptive immune response, one was found that encoded for a component of the major histocompatibility complex (MHC) class I (hla-UBA).

A component of the JNK pathway, MAP3K9, was classed as the highest scoring mapped molecule by IPA assessment of fold-change regulation in Ad5 E1-TC compared to untransformed BRK cells and plays a role in the merged high scoring networks.

A key component of the class was a fall break trip to Brazil to visit the 32nd São Paulo Bienal.