The determination that Dhh1p (and its human ortholog, DDX6) is an essential component of processing bodies that are sites of mRNA decay [46] [47] allows us to functionally link transcription elongation arrest by DNA damage to mRNA export and decay through BRCA1 and P-CTD cleavage (Fig. 6E).
Nucleolar localization was verified by co-immunostaining of the nucleolar marker protein Fibrillarin, which is a component of the rRNA processing machinery.
Slowed processing speed in LLD may be specific rather than general, which underscores the need to link components of processing speed to underlying neural circuitry.
Exact addition in L2 requires additional cognitive components of processing L2 auditory verbal numbers and translating those numbers into L1.
Interestingly, maternal loss of Dgcr8, a component of the miRNA processing pathway, is without effect on development, even though the profile of misexpressed miRNAs in maternal Dicer -/- and Dgcr8 -/- zygotes is the same [ 28].
Knockdown of NELF or a component of the histone 3′ processing machinery blocks histone pre-mRNA cleavage at the correct sites, resulting in an accumulation of aberrant polyadenylated histone mRNAs20,37,38.
EWS is a component of the Drosha/DGCR8 miR processing complex, and the copy number of the wild-type intact form is reduced in Ewing's sarcomas with EWS-containing fusions.
To assist process and product design, a method has now been developed for predicting the decay of severity of Type 2 defects during processing, for a component of given shape and process history.
As a highly automated system designed to run as a stand-alone package or as a component of other Landsat data processing systems, this system can be used to assess the quality of essentially every Landsat surface reflectance image where spatially and temporally matching MODIS data are available.
The affect-as-information model (Clore et al. 2001) indicates that affective feelings as a component of input in information processing can provide information and serve as crucial cues to guide judgment and decision making; therefore, affective feelings can lead to a higher or lower evaluation of a certain object.
Additionally, it has been identified as a component of the small RNA processing pathway.
