Although there is a genetic component in the pathogenesis of epilepsy, the molecular mechanisms of this syndrome remains poorly understood.
These results suggest a microvascular component in the pathogenesis of this condition.
Furthermore, studies of identical twins suggest a genetic component in the pathogenesis of nephropathy in T2DM, and less so in T1DM [19].
Loss of tolerance to self-antigens is a critical component in the pathogenesis of autoimmunity.
Several studies have shown that IGF is a key component in the pathogenesis of NICTH.
Hyperglycemia and insulin resistance have long been considered a central component in the pathogenesis of DCM [ 29, 30].
Indeed, a disturbed skin barrier is an important component in the pathogenesis of contact dermatitis, ichthyosis, psoriasis, and atopic dermatitis.
Disruption of any of these essential processes is an important component in the pathogenesis of many diseases, including cancer.
Th2-dominated inflammatory response in the airway is an integral component in the pathogenesis of allergic asthma.
Loss of differentiation is an important component in the pathogenesis of many cancers.
