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The hTERT core promoter and sequences upstream contain numerous binding sites for positive and negative regulators of transcription suggesting a complex regulation (Takakura et al, 1999).
They have a complex regulation and they play essential roles in regulating the actin-cytoskeleton, as indicated by the presence of an actin-binding domain in their C-terminus (reviewed in [ 44]).
The study also suggests a complex regulation of SHN2 gene.
Moreover, only 36 of the essential genes were identified as NF-κB pathway targets, suggesting a complex regulation of a focused transcriptional pathway output paradigm.
The time delay between the initial stimulus and the cumulative elevation of c-fos messenger RNA suggests a complex regulation from mechanoreception to c-fos gene expression.
Mycotoxin formation is subjected to a complex regulation, but it is often induced by nutrient limitation (Demain 1986).
This modification by a 76 amino acid ubiquitin (Ub) determines protein turnover, regulation and molecular function, and provides a complex regulation of various biological processes ([Hershko and Ciechanover 1998]).
Those findings suggest a complex regulation of c-Myc induction, which might support the cancer phenotype.
Its expression is very dependent on the growth conditions, suggesting a complex regulation.
We reason that this upregulation represents a complex regulation of GATA4 transcription factor during development.
These results may suggest a complex regulation of CCL25 and CCL28 mRNA expression.
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