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Muslim resentment of the West has a complex pathology, dating back to the Spanish reconquista in medieval times; that is hardly something that can be undone.
Large segmental defects of long bones comprise a complex pathology resulting from a variety of aetiologies.
Schizophrenia is a complex pathology that may involve, among its many signs and symptoms, severe delusions and hallucinations.
These mortalities are most often associated by a combination of drug side effects and a complex pathology status of the patient.
Spinal cord injury (SCI) is a complex pathology that evolves after primary acute mechanical injury, causing further damage to the spinal cord tissue that exacerbates clinical outcomes.
However, degenerative disease of the spine is a complex pathology involving not only the vertebral bodies, the intervertebral discs and the facet joints but all the spinal elements (flaval ligaments, interspinous ligaments and posterior vertebral elements) as well.
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Anemia is a marker for a more complex pathology which resembles human haemophagocytic syndrome: hepatosplenomegaly, pancytopenia and a large number of hyperactivated phagocytosing macrophages in bone marrow, liver and other tissues.
In conclusion, translational animal research plays critical roles in helping researchers to understand the mechanisms of the disease, in improving the methods of early detection, and in identifying and investigating potential treatment targets for such a common, complex pathology as OA.
Nevertheless, since the cause of LOAD is multifactorial [ 36], it is improbable that single (protein) markers can accurately define this complex pathology; an algorithm based on multiple biomarkers should deliver a more accurate clinical diagnosis [ 35].
The guinea pig model was studied, which shows more complex pathology with a heterogeneity of lesion types and stages within one animal at any one time.
This complex pathology results from a deregulated inflammatory response by the IIS following a systemic bacterial infection.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com