HA33 was shown to disrupt epithelial tight junctions from the basolateral side, promoting rapid toxin complex passage via a paracellular mechanism (Fujinaga et al., 2009; Jin et al., 2009).
But another way to immerse myself in Sondheim's work is to play through the piano-vocal scores, where I can linger on some pungent harmony, unravel layered contrapuntal lines, slow down a complex rhythmic passage to see how it works, or trace the contours of a beguiling melody.
The German bore and the choked mouthpiece also facilitate complex passage work and can deliver a more massive tone.
As the Secretary-General has pointed out, the knowledge, the resources and the strategies already exist to give children the best possible start in life, a quality primary education - and help in navigating the complex passage from adolescence to adulthood.
For if we know anything, it is that in a $30 trillion global economy, the knowledge, the resources and the strategies already exist to give children the best possible start in life, to educate them, and to help them navigate the complex passage from adolescence to adulthood - outcomes that are crucial first steps if we are to break the endless cycle of global poverty.
For if we know anything, it is that in a $30 trillion global economy, the knowledge, the resources and the strategies already exist to give children the best possible start in life, educate them, and help them navigate the complex passage from adolescence to adulthood - outcomes that are crucial first steps if we are to break the endless cycle of global poverty.
For if we know anything, it is that in a $30 trillion global economy, the knowledge, the resources and the strategies already exist to give children the best possible start in life - which begins with breastfeeding and immunization and then is followed by early care and protection; education; and help in navigating the complex passage from adolescence to adulthood.
This month: a picture-labeling activity to build vocabulary; a video-making challenge inspired by a Times piece about a piano; a sequencing exercise for understanding complex passages; and, finally, a "noisy, fun, and rambunctious learning game well worth the organized chaos that ensues".
The grass mound hides a complex of passages and chambers built of carefully crafted slabs of sandstone that in scale and accomplishment has few equals in prehistoric Europe.
The other approach was the contrapuntal fantasia, in which long, complex passages of counterpoint evolve with a miraculous blend of compositional rigor and improvisatory freedom.
