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The centromeric regions of chromosomes found in higher eukaryotes are a complex motif of repetitive sequences.
To summarize, the pair-distance histogram method is poorly efficient to highlight the periodic presence of a complex motif.
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Thus, in scenarios where imputation is not possible, enzymes with a long, complex motif resulting in a more limited set of covered sites may be desirable.
We desire a model for TFBSs and genomic sequence that supports a more complex motif representation without losing the ability to characterize sequence wide properties, which means a flexible feature design.
These repeats are based on a more complex motif and are longer than SSRs.
Hence, a motif-complexity score was proposed in [ 17] to filter out models with lower complexities, that is, (1) c (M ) = 1 4 k ∏ ∀ b i ∈ χ k ∑ i = 1 k f (b i, i ) Σ i = 1 k f (b i, i ), where k is the length of k-mers and f(b i, i) is the observed frequency of the base b i at position i in the model M. Here, the complexity score lies in [(1/4) k, 1], where 1 refers to a fully complex motif PFM.
However, our sequence word aligner failed to extract any complex motifs from the coding sequence model (for either strongly bound or weakly bound genes).
One unique feature of the BRCA1 A complex is that multiple ubiquitin binding motifs exist in the BRCA1 A complex.
The removal of the temporary silicon linkage unravels a complex structural motif containing multiple stereogenic centers.
DM1 is caused by expansion of a (CTG n repeat in the DMPK gene, while DM2 is caused by expansion of a (CCTG n part of a complex repetitive motif (TG n TCTG n CCTG n in the ZNF9 gene.
Our results clearly demonstrate that nuclear export of Atx3 is dependent on a complex Atx3 motif, located in the N-terminal portion of the protein, which requires the context of the Josephin domain plus the ubiquitin-interacting motifs.
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