TF expression by tumour cells allows for the formation of the extrinsic tenase complex; establishment of the intrinsic tenase and prothrombinase complexes on the surface of various tumour cell lines has also been described, mainly associated with PS exposure [ 27– 31].
Gene regulation in eukaryotes is a complex process entailing the establishment of transcriptionally silent chromatin domains interspersed with regions of active transcription.
These data may be valuable for the establishment of a complex CELSS in the future.
Citizens were sated with decent wages, generous overtime pay and innovative pension plans — that is, through the establishment of a complex, if absolutely amoral, welfare state.
The Glorious Revolution resulted in the abdication and exile of James II and the establishment of a complex form of balanced government in which power was divided between the king, his ministers, and Parliament.
Our structural and thermodynamic analyses have led us to the conclusion, having once ruled out any possible ionization events or conformational changes coupled to the association, that the establishment of a complex hydrogen-bond network mediated by water molecules buried at the binding interface is responsible for the observed thermodynamic behaviour.
Generally, the establishment of a complex microenvironment involving not only the chronic and massive presence of neutrophils but also large populations of bacteria (and/or fungi) in the airway lumen may increase the metabolic share taken by the lung, at the expense of other organs [141].
Since the cellular details of the olfactory neuron-glia interactions differ slightly in different species and are so well characterized in developing M sexta, we seek to elucidate the underlying molecular interactions in this species as the basis for a thorough understanding of the bidirectional conversation between neurons and glial cells in the establishment of a complex neuropil.
Embryo implantation is a complex, synchronized process that requires establishment of a reciprocal dialogue between a receptive endometrium and developing blastocysts.
First, the origin of such a function does not require the establishment of a complex structure ab initio; only a moderate binding affinity of RNA or a short peptide would suffice to provide the starting point for evolutionary selection.
These observations suggest that the establishment of a complex dendritic arbor not only requires instructive cell surface molecules but also physiological UPR to increase the protein folding capacity and maintain cellular homeostasis.
