Adolescence is a complex development phase of marked psychosocial, behavioural, physiological and cognitive changes [ 1, 4] that exacerbate the challenges of an HIV-positive status and the requirement to adhere to a structured treatment regimen.
"It is very difficult to forecast in such a complex development project any kind of realistic date and cost," he said.
This may imply a more complex development of breast cancer and NSCLC compared to colon cancer and ccRCC, or alternatively, it may be due to the heterogeneous histopathological features within their corresponding datasets.
This paper presents an overlapping process model to analyze the impact of process structure on the lead-time of a complex development project.
Again, a Bayesian adaptive approach may offer the best strategy to address the unusually complex development of an autologous anti-tumor vaccine.
And that's without getting into the metaphysics of time travel, the self-updating allegory of technological anxiety, "The Sarah Connor Chronicles" on television or the complex development of a malignant military application called Skynet.
In Mecca, the Masjid al-Haram, the holiest site in Islam and a place where all Muslims are supposed to be equal, is now overshadowed by the Jabal Omar complex, a development of skyscraper apartments, hotels and an enormous clock tower.
Recent evidence suggests a complex temporal development pattern of both emotional and cognitive skills, but linking these development patterns to the real-world decisions that adolescents make has been challenging.
The pipeline is dependent on a complex drug-development ecosystem of academic laboratories, federal funding agencies, biotechnology companies, venture capital, philanthropy, trial sites, contract research organizations, pharmaceutical companies, advocacy groups, and regulatory agencies.
The move was the latest in a series of complex developments on voter registration in the key battleground state of Florida, the state which famously decided the 2000 election in which George W. Bush beat Democrat Al Gore after a legal battle over Florida's results that went to the Supreme Court.
