Sentence examples for a complex and significant from inspiring English sources

The key is that over the last decade, games have progressed from being seen as a geeky pastime for adolescent boys, to being understood and appreciated as a complex and significant artform.

As a result of multiple land use types, spatial heterogeneity, and conflicts of interest among multiple participants, multi-site land use allocation becomes a complex and significant optimization issue.

Subvalvular aortic stenosis is a complex and significant congenital heart disease observed in both dogs (Buchanan 1999; Tidholm 1997) and human beings (Valeske et al. 2011).

We also observed high levels of retained intron and mutually exclusive exons events, confirming a complex and significant effect of ERs on the regulation of RNA splicing in these cell lines.

He was consecrated by means of a complex and highly significant ritual; he was Indra and other gods (deva) incarnate.

The ratification process is sure to be challenging from both ends, but the fact that Presidents Medvedev and Obama achieved such a complex and globally significant deal should be lauded as a genuine achievement.

Parenting adolescents is a complex, challenging and significant life task and the PPAP may be seen as an important resource for supporting parents in their vital parental role.

Cardiac resynchronization therapy (CRT) is currently indicated in patients with moderate to severe heart failure, a wide QRS complex and significant left ventricular dysfunction despite optimal medical therapy.

The use of Natural Fibers in cementitious composites is an innovative technical solution but, they are characterized by a complex microstructure and significant heterogeneity, which influence their interaction with cementitious matrices, whose identification requires further advances in the current state of knowledge.

Extending or restructuring the internal signaling network of a process can introduce complex and significant transient dynamics that cannot be accurately described by eq 1.

JILL THOMPSON, Queens, posted on nytimes.com JOHN LE CARRÉ HAS NOT MELLOWED WITH AGE John le Carré is too complex and significant a novelist to deserve this superficial "portrait," which reads as if Dwight Garner is anxiously petting an old cat, careful to avoid a snarl.