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The phrase "a completely distinct mode" is correct and usable in written English.
It can be used to describe a method or manner that is entirely different from another.
Example: "In this study, we will explore a completely distinct mode of communication that has emerged in digital spaces."
Alternatives: "an entirely different method" or "a wholly separate approach."
Exact(1)
Indeed, OBP from insect in a separate order (Lepidoptera) have a completely distinct mode of action, which has been well-documented in the literature [7], [8], [10], [12], [15], [16], [18], [19].
Similar(57)
I've been working on a novel for a few years now, one set a hundred years ago and written in a completely distinct style.
"Evzio is a completely distinct way of using Naloxone, because it talks," she said.
We're lucky: we have a completely distinct policy on independence, which helps us a lot".
(Since you're wondering, the iPhone uses a "speech bubble" icon for messaging, and a completely distinct envelope icon for email. No chance of confusing the two).
UCbase 2.0 represents a completely distinct application with significantly different characteristics and scopes.
Each level of methylation of these two residues has a completely distinct profile.
None of the super-orders represented by taxon sequences fell into a completely distinct cluster.
Noteworthy, although cyanobacterial aconitase formed a completely distinct and isolated cluster, yeast aconitase grouped with aconitase from animals.
We are a third thing, a distinct mode of transportation, requiring different practices and different rules.
A very distinct mode of interaction with the two model systems was observed.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com