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The phrase "a completely different structure" is correct and usable in written English.
It can be used when discussing variations or changes in form, organization, or arrangement in various contexts, such as architecture, writing, or systems.
Example: "The new design proposal features a completely different structure compared to the original plan, emphasizing sustainability and efficiency."
Alternatives: "an entirely distinct framework" or "a wholly different arrangement".
Exact(20)
The difference is that a short story usually has a completely different structure to a novel, whereas the short novel is basically what it says – a miniature version of a full length novel.
A remarkable observation is that amino acids that coevolved in one group of bacteria are located in a completely different structure face to those detected in another group of bacteria, while both keeping structural continuity.
"But now we can communicate fluidly," he said, "even with companies that have a completely different structure".
He added: "They want a completely different structure of the university".
There will have to be a completely different structure, which will be difficult when the whole thing about Twitter is its spontaneity.
But the symphony is a completely different structure, both in terms of how it is made, and what Max is trying to do in the piece.
Similar(40)
DC120 has completely different structure from A-443654 and GSK690693 and also induces AKT hyperphosphorylation, which may be because of the above-mentioned conformational change by the inhibitor itself, at least partly.
People, he noted, were saying that the watch's face was made of "sapphire glass": "It's not glass, it's sapphire crystal — completely different structure.
In some other cultures the basic household can have completely different structure (for example many generations sharing the same dwelling), and therefore this kind of approach can give rise to potential bias without any additional information about the structure of complex households.
By contrast, VrPPase has a completely different gate structure due to the shift in the position of the semi-conserved glutamate.
Companies might instead create a completely different funding structure for transformational innovation, one that's separate from the regular P&Ls of the business.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com