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The phrase "a completely different rationale" is correct and usable in written English.
You can use it when discussing a reason or justification that is entirely distinct from another.
Example: "The committee decided to reject the proposal because they had a completely different rationale for their funding priorities."
Alternatives: "an entirely different reason" or "a wholly distinct justification".
Exact(1)
Based on the Chinese diagnostic patterns, i.e., inspection, listening, smelling, inquiry, and palpation, the CHM prescription follows a completely different rationale than many western drug treatments [ 15].
Similar(59)
The action of uncouplers and inhibitors of oxidative phosphorylation has been explained by a fresh and completely different rationale.
A completely different tour".
With a completely different flavor.
A final is a completely different game.
"they are a completely different product".
"This is a completely different ballgame.
But it's a completely different life".
Daytime is a completely different story.
"It was a completely different experience".
It's a completely different life".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com