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The phrase "a completely different method" is correct and usable in written English.
You can use it when discussing an alternative approach or technique that is distinct from the one previously mentioned.
Example: "After reviewing the results, we decided to implement a completely different method to achieve better outcomes."
Alternatives: "an entirely different approach" or "a wholly distinct technique."
Exact(16)
Obviously the manager of each institution uses a completely different method of evaluating the success of the performers in their charge.
Now, the news: Researchers at Yale and Carnegie Mellon universities have published a paper in Nature Communications revealing a completely different method of editing genes and targeting mutations that cause diseases.
According to Sidhu, compared to using tensiometers, farmers were less enthusiastic about direct seeding, probably because it requires a completely different method of cultivation over conventional practices, and germination failure can also be an issue.
By a completely different method, relying on complex analysis, we prove that this still holds when T>4.2L/M if M>0 and when T>6.1L/|M| if M<0.
However, in this period he also presented a completely different method, which did not rely on the SZA but rather on the ergodic hypothesis.
Nothing is expanded to show more options, nothing is made more suitable for selection by mouse, nothing has been done that acknowledges that PC gamers have a completely different method of navigating these menus.
Similar(44)
Our conclusions resemble those of a study that used completely different methods.
Indeed, when it comes to displaying Craigslist listings on a map, CLMapper and PadMapper use two completely different methods.
Bottle-feeding may result in "nipple confusion" [ 26], for it is a completely different feeding method regardless of attempts to make bottle-feeding more closely resemble breast-feeding.
Absolute quantification would be crucial for obtaining advanced biological conclusions and conformation using a completely different analytical method (e.g. mass spectrometry).
The validity of these results was confirmed with exactly matching results by an outside laboratory that independently prepped DNA from the paraffin blocks and utilized a completely different detection method.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com