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Histology showed a complete mole.
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Of the 618 women studied, 547 had a diagnosis of complete mole, 13 complete mole with a twin conception and 58 partial moles.
However, there is 1 report of a definitive androgenetic complete mole that stained positively for p57kip2 [ 3].
The details to diagnosis and assessing GTD were a complex echogenic uterine mass with numerous cystic spaces and no fetus or amnionic sac for complete mole, a thickened and hydropic placenta with fetal tissue for partial mole and nonspecific focal masses with myometrial epicenter which were sonographically indistinguishable from one another for invasive mole and choriocarcinoma.
Can polymer-based immunohistochemical staining of p57kip2 replace DNA analysis as an inexpensive means of differentiating complete mole from partial mole or hydropic abortion?
Another article includes novel information on the clinical usefulness of immunochemistry in the differential diagnosis of an uncommon disease, specifically the complete mole.
We believe this method to be a very useful tool for differentiation of complete mole, when the results of other tests are equivocal.
More disturbing is what's known as a "complete hydatidiform mole," in which, owing to a gross genetic aberration, a placenta develops without a fetus attached to it.
Although 85% of patients with a complete hydatidiform mole achieve spontaneous remission after a few months, 15% of them will experience gestational trophoblastic neoplasia, which requires chemotherapy.
Histology showed a complete hydatiform mole.
Most (86.90%) cases were diagnosed with a complete hydatidiform mole (CHM).
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