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The phrase "a complete disruption of" is correct and usable in written English.
It can be used to describe a total interruption or breakdown of a process, system, or situation.
Example: "The storm caused a complete disruption of the transportation network, leaving many travelers stranded."
Alternatives: "a total breakdown of" or "an absolute interruption of".
Exact(28)
A complete disruption of the pancreatic anastomosis is evident (black arrow in b).
A complete disruption of the nerve (2) results in disorganised sprouting of nerve fascicles and fibrous tissue (3).
After that, the SWNTs quality decreases, with a complete disruption of the tubular structure leading to multi-layered polyaromatic carbon materials observed after 50 h.
In addition to antibacterial activity of the silver nanoparticles, a complete disruption of the bacterial membrane of Escherichia coli cells was observed after few minutes in contact with silver nanoparticles under TEM analysis (Raffin et al. 2008).
We observe that EWS-FLI1-transformed murine fibroblasts, as well as human Ewing tumor-derived SK-N-MC cells, exhibit a complete disruption of their actin cytoskeleton, retaining very few stress fibers, focal adhesions and cell-to-cell contacts.
Today, with the rise of the mobile connected consumer, the growing penetration of new technologies and a purchasing process reinvented through social collaboration, retailers face a more challenging, complex environment affected by a complete disruption of the traditional retail business model as we know it.
Similar(32)
A near complete disruption of P. putida KT2440 cells was achieved in the French press within 3-pases at an operating pressure of ~965 bar for a slurry with a biomass concentration of 100 g/L.
Sliding window analysis of the MUA showed that the onset of the second component led to a nearly complete disruption of the ongoing oscillation.
This example of incomplete knockout in mice versus comprehensive knockdown in zebrafish illustrates the utility of zebrafish for obtaining a more complete disruption of gene function in some cases.
Biochemically, ZS patients are characterized by the absence of functional peroxisomes and an almost complete disruption of peroxisomal beta-oxidation, leading to the accumulation of branched and very long-chain fatty acids, abnormal bile acids, and leukotrienes.
Remarkably, siRNA pools targeting 18 splicing factors caused an almost complete disruption of sister chromatid cohesion that was comparable to the loss of SGOL1 or the loss of the core cohesin subunit SCC1 (Fig 3A and B).
More suggestions(16)
a complete perturbation of
a complete breakdown of
a complete rupture of
a complete interruption of
a complete distortion of
a complete alteration of
a complete dislocation of
a complete disorganization of
a complete upheaval of
a complete termination of
a total disruption of
a complete disintegration of
a complete review of
a complete flood of
a complete distrust of
a major disruption of
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com