Sentence examples for a complementary target from inspiring English sources

We hypothesized that D4 receptor could be a complementary target in designing new antipsychotics, mainly because of its predominance in parvalbumin interneurons.

Similarly, designed miRNAs were also excised from transcripts encompassing artificial miRNA precursors and could inhibit the expression of mRNAs containing a complementary target site.

RNA interference (RNAi) is a cell process in which a short interfering RNA (siRNA) of 21 25 bp guides the degradation of a complementary target mRNA.

With the hybridisation of a complementary target sequence (BPV target), the electrochemical signal decreased compared to a BPV probe immobilised on the modified PLL-gold electrode.

a In the presence of a complementary target T3, P3 reacts with T3 to form a P3 T3 complex, which detaches from the GO surface, resulting in the fluorescence "on" state.

Compared to RRE IIB RNA, these two types showed noticeable difference and demonstrate that the electrochemical biosensor based on VSNEA is effective in signaling the presence of a complementary target and discriminating targets from a single base-pair substitution mutation.

A miRNA directed against a perfectly complementary 3' UTR target site also results in mRNA degradation [ 15, 16], indicating that a miRNA can function in the RNAi pathway given a perfectly complementary target site.

They first calculated the optimal free energy of an miRNA when the entire miRNA binds to a perfectly complementary target site.

The input output transfer curve of the FET is extracted for different surface configurations including DNA probe, DNA probe hybridized with a match (complementary) target and DNA probe coated with un-match DNA sequence.

Ni et al. [ 68] showed that overexpression of miR394a in Arabidopsis reduced the transcript of an F-box gene (At1g27340, also known as LEAF CURLING RESPONSIVENESS, LCR) containing a miR394 complementary target site.

The target prediction parameters were used according to Schwab et al. [ 60]: no mismatch at positions 10 and 11, no more than one mismatch at positions 2 12, no more than two consecutive mismatches downstream of position 13, and at least 72% of free energy compared to a perfectly complementary target.