The phrase "a complementary site" is correct and usable in written English.
It can be used in contexts where you are referring to a location or resource that enhances or completes another site, often in fields like biology, ecology, or web development.
Example: "The research team discovered a complementary site that provided additional data to support their findings."
Alternatives: "an auxiliary site" or "a supplementary site".
The 3′UTR of CCND3 mRNA contained a complementary site for the seed region of miR-138.
The NAC genes contain a complementary site with miR164, which were negatively regulated by miR164 through mRNA cleavage (Sieber et al., 2007).
Computational target prediction is primarily based on potential pairing of the miRNA seed sequence to a complementary site in the 3′ UTR of a target mRNA according to specific base-pairing rules.
According to this rationale, PTEN was selected as the candidate target gene of miR-20b, which was highly conserved among different species and whose 3′-UTR of mRNA contained a complementary site for the seed region of miR-20b.
The 3′-UTR of SENP1 mRNA contained a complementary site for the seed region of miR-145 (Fig. 3a), and the highly matched bases attract our attention to investigate whether SENP1 is a putative target of miR-145.
During the past two decades, numerous studies have identified and emphasized the importance of microRNAs (miRNAs), which are endogenous small noncoding RNAs that regulate gene expression by pairing with a complementary site in the 3′UTR to interfere with the translation or stability of target transcripts (Jackson & Linsley, 2010).
Co-transfection of miR-145 duplex with a luciferase reporter containing a perfect complementary site to the mature miRNAs resulted in a marked downregulation of the luciferase activity, demonstrating a highly effective overexpression (FIGURE S2A).
The effect of miR-143 duplex transfection in DLD-1 cells was confirmed by co-transfection of a luciferase reporter containing a perfect complementary site to the mature miR-143 (Additional file 2: Figure S2).
Setting its sights on becoming the Salesforce.com for doctors and the Facebook for health, last month the company launched Patient Fusion — a new complementary site that allows anyone and everyone to compare doctor reviews and book appointments within an hour of arriving at the doctor's office.
For example, Enright et al. reward for multiple sites by summing a score for all complementary sites in the target 3' UTR, whereas our algorithm requires a miRNA/target pair to have a user-specified absolute number of target sites each meeting a user-defined set of biological constraints.
However, it has been reported that siRNA-mediated translational inhibition can be induced by an incomplete complementary site in the ORF region of a mammalian reporter gene, which means that the target sequence of a given miRNA is not only in the 3′-untranslated region.
