This modular concept, based on the strengths of mass spectrometers operating with both MALDI and ESI, provides an alternative and complementary route for building powerful mass spectrometric tools for the biological research.
Solid-state nuclear magnetic resonance (ssNMR), which can elucidate the functional groups and cross-link sites within intact polymers, provides a complementary investigative route.
This result suggests that the living environment, farm milk and having a dog could offer alternative, possibly complementary routes of protection against allergies.
We show that Sgt1 bridges the Hsp90 molecular chaperone system to the substrate-specific arm of SCF ubiquitin ligase complexes, suggesting a role in SCF assembly and regulation, and providing multiple complementary routes for ubiquitination of Hsp90 client proteins.
Among the complementary routes available, in vivo pathway engineering, also referred to as 'combinatorial biosynthesis', is an emerging method that relies upon the co-expression of sugar biosynthetic gene cassettes and glycosyltransferases in a host organism to generate novel glycosylated natural products.
Both routes, reduction of food intake and increase in physical exercise are valuable complementary routes in the battle against obesity.
2, 3 Consequently, it is desirable that complementary routes become available, particularly for proteins that are not anticipated to express as soluble and folded intein fusion proteins.
Two complementary routes leading to programmed cell death have been characterized, namely, the caspase-dependent and caspase-independent pathways, which differ in the events needed to trigger the apoptotic cascade [ 9].
This approach may be used as a complementary, relatively simple route to assess suberin genetic engineering strategies towards resistance to environmental stress.
