Exact(34)
Pallikkuth, S. et al. Phosphorylated phospholamban stabilizes a compact conformation of the cardiac calcium-ATPase.
First, we verified that individual ∆NTEO adopts a compact conformation equivalent to that in OCPO.
Upon phosphorylation, a dramatic change involving a transformation from a compact conformation to an extended conformation is found in the heavy NF (NF-H) protein.
The highly hydrophobic copolymers are characterised by a compact conformation in aqueous solution, due to the formation of intrachain hydrophobic aggregates.
Furthermore, hybrid molecular dynamics and steered molecular dynamics simulations validated that BMP-2 tightly anchored on the HAP-Pol surface with a relative loosened conformation, but the HAP-Sin surface induced a compact conformation of BMP-2.
Both AM-2, which had a proline linker, and AM-3, which had an aminocaproic acid linker, adopted a compact conformation in water and a bent conformation in membranes.
Similar(26)
Introducing a more hydrophobic moiety can offer a more compact conformation and a more discontinuous phase.
SANS data show both a more compact conformation for a copolymer guest molecule than for a linear guest and also a smaller molecular expansion with increasing molecular weight when both guest and host are copolymers.
These strong interactions facilitate GLUT4 to attain a more compact conformation with a reduced pore size compared to either apo or glucose bound forms (compare Figure 4A, 4B and 4C).
In this case, disorder derives from a lack of specificity for a single compact conformation as instead heterogeneous ensembles of conformations with similar stabilities and compactness are formed.
These specific rearrangements lead to a more compact conformation resulting in a 5% decrease in the volume of the LBP compared to 1α,25(OH)2D3.
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